Participate in Alzheimer's Research

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HOPE - Actively Enrolling

Recruitment Coordinator: Nicole Gullotti

Phone: 617-358-5382

Email: ngullott@bu.edu

 

Goal: This study aims to collect a longitudinal set of data on a large, diverse group to advance our knowledge on the diagnosis, prevention and treatment of Alzheimer’s disease and related disorders.

Time Commitment  - The HOPE study takes place yearly with an in-person visit at one of two study locations in Massachusetts.  Each year's visit will take approximately 2 days to complete 

Location - Participation can occur at either Boston University Medical Center, or Boston University Neurology Associates at Wingate Residences at Needham.

Eligibility - Adults over the age of 55 who fit into three study groups:
1) Healthy Adults
2) Alzheimer’s Patients
3) Adults with Mild Cognitive Impairment

We are also recruiting participants with a history of contact sports to help us understand how repetitive head impacts affect a person’s risk of developing later-life neurologic disorders. Learn more HERE 


Goal: A longitudinal study designed to investigate the relationships between the clinical, cognitive, imaging, genetic and biochemical biomarker characteristics of the entire spectrum of Alzheimer's disease.

Location - Boston University Medical Center, and other locations across the country.

Eligibility - Male and female participants between the ages of 55 and 90. Learn more about specific eligibility requirements at the study website HERE.

Alzheimer's Disease Neuroimaging Initiative 3 - Actively Enrolling

Recruitment Coordinator: Nicole Gullotti

Phone: 617-358-5382

Email: ngullott@bu.edu


Goal - This clinical trial is testing a new oral medication that may be able to prevent amyloid-beta protein plaques from forming in the brain.

Location - Boston University Medical Center, and other locations across the country.

Eligibility - Healthy adults between the ages of 60 and 75. This study is specifically recruiting asymptomatic individuals with a specific form of a gene called APOE4, which increases a person’s chance of developing Alzheimer’s disease. Learn more about specific eligibility requirements at the study website HERE.

Generations: A Prevention Trial - Actively Enrolling

Recruitment Coordinator: Nicole Gullotti

Phone: 617-358-5382

Email: ngullotti@bu.edu

 


Goal - This study aims to compare Alzheimer’s disease and Chronic Traumatic Encephalopathy.

Time Commitment  - A one-time visit for an hour-long MRI scan

Location of Study - In person at Brigham & Women’s Hospital

Eligibility - Men over the age of 45 who fit into three study groups:
1) Alzheimer’s Patients
2) Former National Football League players
3) Men who have no history of organized contact sports

Learn more HERE 

Cerebral Perfusion and Metabolism in Chronic Traumatic Encephalopathy - Actively Enrolling

Recruitment Coordinator: Nicole Gullotti

Phone: 617-358-5382

Email: ngullott@bu.edu


Goal -. Research suggests that patients with different types of cognitive impairment perform differently on certain tests. The goal of this study is to better understand how different impairments affect perception, thinking and memory, hopefully leading to better diagnostic evaluations.

Location - Jamaica Plain

Eligibility -  Men and women between the ages of 65 and 90 who fit into three study groups:
1) Healthy Adults
2) Alzheimer’s Patients
3) Adults with Mild Cognitive Impairment

Learn more HERE 

Memory in AD - Actively Enrolling

Recruitment Coordinator: Nicole Gullotti

Phone: 617-358-5382

Email: ngullott@bu.edu

 


Goal -  This study is looking to detect changes in the brain associated with aging and cognitive impairment using near infrared spectroscopy (NIRS).

Location - Boston University Medical Center

Eligibility - Men and women between the ages of 18 and 89 who are either cognitively normal or have been diagnosed with Mild Cognitive Impairment. Learn more HERE 

Optical Brain Imaging Research Study - Actively Enrolling

Recruitment Coordinator: Nicole Gullotti

Phone: 617-358-5382

Email: ngullott@bu.edu


Goal - The purpose of this research study is to investigate if patients with early Alzheimer’s disease have periods of abnormal brain activity, such as seizures, that might explain some of their memory problems.

Time Commitment - Participants will be fitted with a cap to monitor their brain activity for 24 hours.

Location -Boston University Medical Center

Eligibility -Men and women between the ages of 50 and 90 who fit into three study groups:
1) Healthy Adults
2) Alzheimer’s Patients
3) Adults with Mild Cognitive Impairment

Learn more HERE 

Subclinical Paroxysmal EEG Abnormalities in Alzheimer’s Disease - Actively Enrolling

Recruitment Coordinator: Nicole Gullotti

Phone: 617-358-5382

Email: ngullott@bu.edu


Goal - Study investigating the use of event-related potentials to diagnose AD in the clinic. Ultimately the project will compare the diagnosis of AD using event-related potential techniques to amyloid PET techniques as a gold standard.

Location - Jamaica Plain

Eligibility -Men and women between the ages of 50 and 100 diagnosed with any memory disorder

Learn more HERE 

Utility of EEG in a Memory Disorders Clinic - Actively Enrolling

Recruitment Coordinator: Nicole Gullotti

Phone: 617-358-5382

Email: ngullott@bu.edu


Goal - This program uses MRI to study the parts of the brain that play a role in spatial navigation, specifically the ability for a person to orient oneself in their surroundings.

Time Commitment  - A one-time visit for an MRI scan

Location - Boston University Medical Center

Eligibility - Men and women between the ages of 20 and 35 or 60 and 80 who are either cognitively normal or have been diagnosed with Mild Cognitive Impairment. Learn more HERE 

Spatial Navigation - Actively Enrolling

Recruitment Coordinator: Nicole Gullotti

Phone: 617-358-5382

Email: ngullott@bu.edu


Goal - This study assesses the relationship between chronic stress and cognition in older African American adults.

Time Commitment  - Participants will answer questionnaires, undergo cognitive testing and provide a saliva sample to measure cortisol levels (a hormone associated with stress)

Location - Boston University Medical Center

Eligibility - Healthy adults between the ages of 55 and 75. Learn more HERE 

Chronic Stress Research Study for African American Older Adults - Actively Enrolling

Recruitment Coordinator: Nicole Gullotti

Phone: 617-358-5382

Email: ngullott@bu.edu


Goal - This study is researching a new non-invasive system designed to measure brain activity by shining a light on a person’s temple and taking a series of measurements while a series of tasks are performed.

Location - Bedford

Eligibility - Adults between the ages of 65 and 90 who have been diagnosed with Mild Cognitive Impairment. Learn more HERE 

The Light Study - Actively Enrolling

Recruitment Coordinator: Nicole Gullotti

Phone: 617-358-5382

Email: ngullott@bu.edu


Goal - This study is investigating whether being physically active is beneficial for cognitive health.

Time Commitment  -Participants will work with a personal trainer for free, 3 times per week for 12 weeks.

Location - Boston University Medical Center

Eligibility - Healthy adults between the ages of 60 and 80. Learn more HERE 

Exercise Intervention Study - Actively Enrolling

Recruitment Coordinator: Nicole Gullotti

Phone: 617-358-5382

Email: ngullott@bu.edu


Goal - It is thought that African Americans are more likely than European Americans to have Alzheimer’s disease. This study aims to examine how psychosocial stress and socioeconomic status contributes to this health disparity.

Location - Because the study takes place over the phone and through mail, you can participate from anywhere in the world. 

Eligibility - Healthy adults between the ages of 65 and 85. Learn more HERE 

Impact of Psychosocial Stress - Actively Enrolling

Recruitment Coordinator: Nicole Gullotti

Phone: 617-358-5382

Email: ngullott@bu.edu


Goal - This study aims to compare electrodermal activity in patients with dementia and control subjects in an effort to better understand what leads to behavioral disturbances in Alzheimer’s disease patients.

Time Commitment - This study visit will last one hour, during which participants will wear monitors on their hands and feet.

Location - Boston University Medical Center

Eligibility - Healthy adults between the ages of 60 and 95. Learn more HERE 

Assessment of Behavioral Associations - Actively Enrolling

Recruitment Coordinator: Nicole Gullotti

Phone: 617-358-5382

Email: ngullott@bu.edu